{"id":405,"date":"2018-04-10T05:09:10","date_gmt":"2018-04-10T05:09:10","guid":{"rendered":"https:\/\/www.saratoga.com\/healing-health-wellness\/?p=405"},"modified":"2022-10-07T17:53:16","modified_gmt":"2022-10-07T17:53:16","slug":"a-review-of-the-estrogenic-essential-oils-clary-sage-oil-part-ii","status":"publish","type":"post","link":"https:\/\/www.saratoga.com\/healing-health-wellness\/2018\/04\/a-review-of-the-estrogenic-essential-oils-clary-sage-oil-part-ii\/","title":{"rendered":"A Review of the \u201cEstrogenic\u201d Essential Oils: Clary Sage Oil Part II"},"content":{"rendered":"<p><strong>The Science to Set the Saga Straight\u2026Hormonal Effects and Essential Oils<\/strong><\/p>\n<p><strong>\u00a0\u00a0 <img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-410\" src=\"https:\/\/www.saratoga.com\/healing-health-wellness\/wp-content\/uploads\/sites\/125\/2018\/04\/facts-set-straight-300x200.png\" alt=\"\" width=\"300\" height=\"200\" srcset=\"https:\/\/www.saratoga.com\/healing-health-wellness\/wp-content\/uploads\/sites\/125\/2018\/04\/facts-set-straight-300x200.png 300w, https:\/\/www.saratoga.com\/healing-health-wellness\/wp-content\/uploads\/sites\/125\/2018\/04\/facts-set-straight-768x512.png 768w, https:\/\/www.saratoga.com\/healing-health-wellness\/wp-content\/uploads\/sites\/125\/2018\/04\/facts-set-straight-1024x682.png 1024w, https:\/\/www.saratoga.com\/healing-health-wellness\/wp-content\/uploads\/sites\/125\/2018\/04\/facts-set-straight.png 1280w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/>\u00a0\u00a0<\/strong><\/p>\n<p>Last week, I continued in soapbox-style to set the saga straight regarding essential oils and hormonal support. I further <a href=\"http:\/\/dr-lobisco.com\/male-boobs-essential-oils-lavender-tea-tree-hormones-endocrine-disruption\/\" target=\"_blank\" rel=\"noopener\">debunked the negative claims inferred by the latest study<\/a> that labeled lavender and tea tree oils as potential endocrine disruptors. I summarized what factors to consider when determining if an essential oil will impact hormonal balance by relating them to several of the pitfalls in this study.\u00a0 Knowing these determinants is applicable to understanding these secondary metabolites\u2019 specific effects and if they apply to human beings and\/or oneself.<\/p>\n<p>In the introduction to my next series of articles on \u201cestrogenic\u201d <a href=\"http:\/\/dr-lobisco.com\/science-set-saga-straight-hormonal-effects-essential-oils-clary-sage-estrogen\/\" target=\"_blank\" rel=\"noopener\">essential oils that highlighted clary sage<\/a>, I also provided a list of resources for safe use and potential medication interaction information (<a href=\"https:\/\/www.saratoga.com\/healing-health-wellness\/2018\/04\/the-science-to-set-the-saga-straight-hormonal-effects-and-essential-oils-an-introduction\/\" target=\"_blank\" rel=\"noopener\">found here)<\/a>.<\/p>\n<p>The<a href=\"http:\/\/dr-lobisco.com\/straight-from-the-science-and-into-common-sense-reviewing-and-understanding-hormones-and-essential-oils\/\" target=\"_blank\" rel=\"noopener\"> weekend\u2019s oily tip summarized<\/a> the key findings of my research that demonstrated that clary sage oil has diverse actions, but there is NO evidence that it is estrogenic. I also gave my take-home tips on how to use essential oils for hormonal balance safely. These included:<\/p>\n<p><strong> 1. Reviewing the Evidence with a Critical Eye<\/strong><\/p>\n<p>Don\u2019t be scared by sagas and media hype. Ask yourself these key 3 questions when researching an essential oil and getting frightened by unfounded headlines:<\/p>\n<ul>\n<li>Was it using essential oils or isolates?<\/li>\n<li>Was it done in humans?<\/li>\n<li>Was it following the proper use of the essential oil?<\/li>\n<\/ul>\n<p><strong> 2. Proper and Safe Use<\/strong><\/p>\n<p>Use <a href=\"https:\/\/www.saratoga.com\/healing-health-wellness\/2018\/04\/the-science-to-set-the-saga-straight-hormonal-effects-and-essential-oils-an-introduction\/\" target=\"_blank\" rel=\"noopener\">this link<\/a> to learn more on how to use essential oils wisely and safely and about potential medication interactions. \u00a0Here are some key points:<\/p>\n<ul>\n<li>use proper dosage and application<\/li>\n<li>monitor any drugs that need to remain at specific levels<\/li>\n<li>consider the fact that lab testing has limits, so base your decisions on the whole clinical picture<\/li>\n<\/ul>\n<p><strong> 3. Remembering the Synergism of Essential Oils for Balancing the System<\/strong><\/p>\n<p>Essential oils act differently than isolated, synthetic compounds in the body. Those of high quality and therapeutic action, when used properly, have an innate intelligence that seems to always promote health.<\/p>\n<p>In the <a href=\"http:\/\/dr-lobisco.com\/straight-from-the-science-and-into-common-sense-reviewing-and-understanding-hormones-and-essential-oils\/\" target=\"_blank\" rel=\"noopener\">weekend oily tip blog<\/a>, I also provided my experience of how I use essential oils in my clinic and with my team members. (You can now access a 12-minute video review of all these concepts <a href=\"https:\/\/youtu.be\/tydkn889XqA\" target=\"_blank\" rel=\"noopener\">on YouTube<\/a>.)<\/p>\n<p>Now, I will provide more clinical studies on clary sage which further support the safe use of essential oils for balancing women in hormonal havoc.<\/p>\n<p>&nbsp;<\/p>\n<p><strong><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-409\" src=\"https:\/\/www.saratoga.com\/healing-health-wellness\/wp-content\/uploads\/sites\/125\/2018\/04\/essential-oils-2536471_1280-300x211.jpg\" alt=\"\" width=\"300\" height=\"211\" srcset=\"https:\/\/www.saratoga.com\/healing-health-wellness\/wp-content\/uploads\/sites\/125\/2018\/04\/essential-oils-2536471_1280-300x211.jpg 300w, https:\/\/www.saratoga.com\/healing-health-wellness\/wp-content\/uploads\/sites\/125\/2018\/04\/essential-oils-2536471_1280-768x541.jpg 768w, https:\/\/www.saratoga.com\/healing-health-wellness\/wp-content\/uploads\/sites\/125\/2018\/04\/essential-oils-2536471_1280-1024x721.jpg 1024w, https:\/\/www.saratoga.com\/healing-health-wellness\/wp-content\/uploads\/sites\/125\/2018\/04\/essential-oils-2536471_1280.jpg 1280w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/strong><\/p>\n<p><strong>Clary Sage for Mood Support and Stress in Menopause<\/strong><\/p>\n<p>One<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24802524\" target=\"_blank\" rel=\"noopener\"> small study<\/a> that included 22 menopausal women in their 50\u2019s examined how inhalation of clary sage would impact changes in neurotransmitter concentrations, cortisol, and thyroid stimulating hormone. The researchers reported those who sniffed clary sage had decreased cortisol levels (the \u201cstress\u201d hormone), increased 5-hydroxytrptamine (the monoamine, serotonin), and alleviated mood. All of these were balancing for the individuals effected.<\/p>\n<p><strong>\u00a0<\/strong><\/p>\n<p><strong>Aromatherapy and Menstrual Discomfort<\/strong><\/p>\n<p>In a <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22435409\" target=\"_blank\" rel=\"noopener\">2012 study<\/a>, researchers tested an essential oil blend of lavender (Lavandula officinalis), clary sage (Salvia sclarea), and marjoram (Origanum majorana) in a 2:1:1 ratio diluted in an unscented cream at 3% concentration. The researchers sought to determine this blended cream\u2019s effect on pain relief for menstrual cramps. The subjects massaged the cream on their lower abdomen from the end of one menstruation to the beginning of the next. The author\u2019s concluded:<\/p>\n<p style=\"padding-left: 30px;\"><em>Aromatic oil massage provided relief for outpatients with primary dysmenorrhea and reduced the duration of menstrual pain in the essential oil group. The blended essential oils contain four key analgesic components that amount to as much as 79.29%; these analgesic constitutes are linalyl acetate, linalool, eucalyptol, and \u03b2-caryophyllene. This study suggests that this blended formula can serve as a reference for alternative and complementary medicine on primary dysmenorrhea. (<\/em><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22435409\" target=\"_blank\" rel=\"noopener\"><em>source<\/em><\/a><em>)<\/em><\/p>\n<p>In a preliminary study with high school girls the effectiveness of essential oils for menstrual pain was compared to acetaminophen. According to the authors, \u201c<em>The abdomen was massaged once using clary sage, marjoram, cinnamon, ginger, and geranium in a base of almond oil.\u201d<\/em><\/p>\n<p>The article states, \u201cU<em>sing multiple regression, aromatherapy massage was found to be more highly associated with reduction in the level of menstrual pain than acetaminophen. These finding suggest that aromatherapy massage may be an effective treatment for menstrual pain in high school girls. However, it could not be verified whether the positive effects derived from the aromatherapy, the massage, or both. Further rigorous studies should be conducted using more objective measures<\/em>.\u201d (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3178179\/\" target=\"_blank\" rel=\"noopener\">source<\/a>)<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Clary Sage and Labor<\/strong><\/p>\n<p>Clary sage and chamomile essential oils were evaluated for its efficacy in labor discomfort in midwife care in a study that took place over <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/11033651\" target=\"_blank\" rel=\"noopener\">an eight-year period and included over 8,000 moms.\u00a0<\/a>The authors concluded:<\/p>\n<p style=\"padding-left: 30px;\"><em>The evidence from this study suggests that aromatherapy can be effective in reducing maternal anxiety, fear and\/or pain during labour. The use of aromatherapy appeared to facilitate a further reduction in the use of systemic opioids in the study centre, from 6% in 1990 to 0.4% in 1997 (per woman). Aromatherapy is an inexpensive care option.<\/em><\/p>\n<p>&nbsp;<\/p>\n<p><strong>Three Other activities of Clary Sage<\/strong><\/p>\n<ol>\n<li>Clary sage has been found to <strong>induce relaxation in female patients undergoing urodynamic assessments for urinary incontinence <\/strong>(ouch!). The clary sage oil used was high in linalyl acetate, at a higher percentage than the lavender oil also assessed in the study. This may have accounted for these two particular oils differing effects, as <a href=\"https:\/\/naturalpath.net\/lobisco\/lemongrass-essential-oils-quality-counts\/\">chemotype and quality<\/a> are important indicators of constituents and actions of essential oils.<\/li>\n<\/ol>\n<p style=\"padding-left: 30px;\">According to the authors, \u201cInhalation of clary oil vapors resulted in significantly reduced systolic blood pressure compared with inhalation of lavender oil vapors, similar to findings in patients with gingivitis,13 and suggesting that linalyl acetate, the main component of clary oil, directly relaxed vascular smooth muscles and reduced blood pressure.18\u201d (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3700459\/\" target=\"_blank\" rel=\"noopener\">source<\/a>)<\/p>\n<p style=\"padding-left: 30px;\">(Note, the main constituent was not sclareol, more about that <a href=\"http:\/\/dr-lobisco.com\/tag\/sclareol-clary-sage-estrogen\/\" target=\"_blank\" rel=\"noopener\">here<\/a>.)<\/p>\n<ol start=\"2\">\n<li>In a rat study, clary sage was found modulate dopamine and have mood elevating properties. (source)<\/li>\n<li>Clary sage has also been found to be an antioxidant and microbe-inhibiting. (<a href=\"http:\/\/journals.tubitak.gov.tr\/agriculture\/issues\/tar-04-28-1\/tar-28-1-4-0309-2.pdf\" target=\"_blank\" rel=\"noopener\">source<\/a>, <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4360007\/\" target=\"_blank\" rel=\"noopener\">source<\/a>)<\/li>\n<\/ol>\n<p><strong>\u00a0<\/strong><\/p>\n<p><strong><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-411\" src=\"https:\/\/www.saratoga.com\/healing-health-wellness\/wp-content\/uploads\/sites\/125\/2018\/04\/flower-petri-dish-300x201.jpg\" alt=\"\" width=\"300\" height=\"201\" srcset=\"https:\/\/www.saratoga.com\/healing-health-wellness\/wp-content\/uploads\/sites\/125\/2018\/04\/flower-petri-dish-300x201.jpg 300w, https:\/\/www.saratoga.com\/healing-health-wellness\/wp-content\/uploads\/sites\/125\/2018\/04\/flower-petri-dish-768x515.jpg 768w, https:\/\/www.saratoga.com\/healing-health-wellness\/wp-content\/uploads\/sites\/125\/2018\/04\/flower-petri-dish-1024x687.jpg 1024w, https:\/\/www.saratoga.com\/healing-health-wellness\/wp-content\/uploads\/sites\/125\/2018\/04\/flower-petri-dish.jpg 1280w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/strong><\/p>\n<p><strong>Conclusion<\/strong><\/p>\n<p>I feel that most essential oils influence hormonal balance, but not because they are \u201cestrogenic\u201d or \u201cendocrine disruptors.\u201d It is because they are synergistic and contain many constituents that act in harmony to simultaneously affect the body and brain.<\/p>\n<p>If used safely and responsibly, a blend with clary sage may be helpful to support hormonal issues or symptoms. Be sure to review <a href=\"http:\/\/dr-lobisco.com\/straight-from-the-science-and-into-common-sense-reviewing-and-understanding-hormones-and-essential-oils\/\" target=\"_blank\" rel=\"noopener\">this weekend\u2019s oily tip<\/a> to learn more of these reasons and the points above on synergism.<\/p>\n<p>Now, I will continue with my next hormonal oil to review, fennel oil. <a href=\"https:\/\/dr-lobisco.com\/review-estrogenic-essential-oils-fennel-oil-hormones\/\" target=\"_blank\" rel=\"noopener\">Click here<\/a> to read it.<\/p>\n<p>&nbsp;<\/p>\n<p><em>This material is for information purposes only and is not intended to diagnose, treat, or prescribe for any illness. You should check with your doctor regarding implementing any new strategies into your wellness regime. These statements have not been evaluated by the FDA. (<\/em><a href=\"http:\/\/dr-lobisco.com\/affiliate-disclosure\/\" target=\"_blank\" rel=\"noopener\">Affiliation link.<\/a><em>)<\/em><\/p>\n<p><em>Disclaimer: This information is applicable ONLY for therapeutic quality essential oils. This information DOES NOT apply to essential oils that have not been tested for purity and standardized constituents. There is no quality control in the United States, and oils labeled as \u201c100% pure\u201d need only to contain 5% of the actual oil. The rest of the bottle can be filled with fillers and sometimes toxic ingredients that can irritate the skin. The studies are not based solely on a specific brand of an essential oil, unless stated. Please read the full study for more information.<\/em><\/p>\n<p>Thanks Pixabay and iStock purchases.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The Science to Set the Saga Straight\u2026Hormonal Effects and Essential Oils \u00a0\u00a0 \u00a0\u00a0 Last week, I continued in soapbox-style to set the saga straight regarding essential oils and hormonal support. I further debunked the negative claims inferred by the latest study that labeled lavender and tea tree oils as potential endocrine disruptors. I summarized what [&hellip;]<\/p>\n","protected":false},"author":109,"featured_media":411,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[32,31,30],"tags":[257,253,256,255,254,91,252,89,186,88,25,146,90,258,259],"class_list":["post-405","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-essential-oils","category-holistic-health","category-mind-body","tag-clary-sage-effects","tag-clary-sage-estrogen","tag-clary-sage-labor","tag-clary-sage-menstrual-pain","tag-clary-sage-pms","tag-functional-medicine-glenville-ny","tag-hormones-and-essential-oils","tag-naturopathic-and-functional-medicine-clifton-park-ny","tag-naturopathic-and-functional-medicine-doctor-saratoga-ny","tag-naturopathic-and-functional-medicine-schenectady-ny","tag-naturopathic-doctor","tag-naturopathic-doctor-albany-ny","tag-naturopathic-doctor-ballston-spa-ny","tag-safe-essential-oils-hormones","tag-safety-and-hormones-essential-oils"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\r\n<title>Clary Sage Essential Oil and Hormonal Balance, Is it Estrogenic? 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She became interested in holistic medicine when she was able to heal two herniated discs through nutrition, yoga, supplementation, and chiropractic. She has mentored with holistic practices throughout New York, Vermont, and Connecticut. In addition to her Naturopathic and Functional Medical training, Dr. LoBisco has extensive training in a variety of healing modalities, including therapeutic essential oils, nutraceuticals, herbs, whole food supplements, nutritional medicine, and mind-body therapies. She is a graduate of the accredited, four year post-graduate program in Naturopathic Medicine at the University of Bridgeport in Connecticut. This program includes clinical rotations and a demanding scientific curriculum in integrating conventional and natural medicine. Dr. LoBisco holds her license from the state of Vermont. Dr. LoBisco has completed her postdoctoral training as a certified functional medicine practitioner. She is also certified in Applied Kinesiology and holds a BA in psychology from SUNY Geneseo. She has contributed as an item writer for the North American Board of Naturopathic Examiners (NABNE) and has several articles that have been published in the Naturopathic Doctor News and Review Digest (NDNR) and the Townsend Letter, both physician- based journals. Dr. LoBisco is also a hired speaker on integrative medical topics for medical professionals. Dr. LoBisco currently incorporates her training in holistic medical practices and conventional medicine through writing, researching, private practice, and through her independent contracting work for companies regarding supplements, nutraceuticals, essential oils, and medical foods. She has a small, private wellness consultation practice through telephone and Skype. Dr. LoBisco also enjoys continuing to educate and empower her readers through her blogs and social media. 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