{"id":15872,"date":"2014-11-04T19:55:03","date_gmt":"2014-11-05T00:55:03","guid":{"rendered":"https:\/\/www.saratoga.com\/living-well\/2014\/11\/october-2014-top-holistic-brain-health-news.html"},"modified":"2017-11-28T13:14:21","modified_gmt":"2017-11-28T18:14:21","slug":"october-2014-top-holistic-brain-health-news","status":"publish","type":"post","link":"https:\/\/www.saratoga.com\/living-well\/2014\/11\/october-2014-top-holistic-brain-health-news\/","title":{"rendered":"October 2014 Top Holistic (Brain) Health News"},"content":{"rendered":"

In a few days I’ll heading off to to learn all about one of my favorite subjects, the gut, from some of the top integrative doctors in the world. Specifically, I’ll be flying to Miami for my next module of my functional medicine training!
<\/strong><\/p>\n

I am looking forward to sharing what I learn with all my readers and clients in the upcoming months. In the meantime, I wanted to provide the empowering information I promised via my “Top Holistic Health Reads<\/a>.”<\/strong><\/p>\n

My aim is to keep it sweet, and skim friendly for you, regardless of my nerding-out on all the information I can get my brain around. This month I give lists to highlight the main points on my homepage. <\/strong>If you want to dive more into the information, I also provide the sources and excerpts.
<\/b><\/p>\n

This blog is a special focus for the top health updates related to brain health for October 2014 in which I summarize in the headings below:<\/b><\/p>\n

Integrated Protocol Is a Success with Cognitive Impairment- Case Studies<\/strong><\/p>\n

This
\n report describes a novel, comprehensive, and personalized therapeutic
\nprogram that is based on the underlying pathogenesis of Alzheimer’s
\ndisease, and which involves multiple modalities designed to achieve
\nmetabolic enhancement for neurodegeneration (MEND). The first 10
\npatients who have utilized this program include patients with memory
\nloss associated with Alzheimer’s disease (AD), amnestic mild cognitive
\nimpairment (aMCI), or subjective cognitive impairment (SCI). Nine of the
\n 10 displayed subjective or objective improvement in cognition beginning
\n within 3-6 months, with the one failure being a patient with very late
\nstage AD. Six of the patients had had to discontinue working or were
\nstruggling with their jobs at the time of presentation, and all were
\nable to return to work or continue working with improved performance.
\nImprovements have been sustained, and at this time the longest patient
\nfollow-up is two and one-half years from initial treatment, with
\nsustained and marked improvement. These results suggest that a larger,
\nmore extensive trial of this therapeutic program is warranted. The
\nresults also suggest that, at least early in the course, cognitive
\ndecline may be driven in large part by metabolic processes. Furthermore,
\n given the failure of monotherapeutics in AD to date, the results raise
\nthe possibility that such a therapeutic system may be useful as a
\nplatform on which drugs that would fail as monotherapeutics may succeed
\nas key components of a therapeutic system.<\/em><\/p>\n

Bredesen DE. Reversal of cognitive decline: A novel therapeutic program. Aging. September 27, 2014. <\/p>\n

Wetherby,
\n C. Can Dementia be Defeated Naturally? Small clinical study finds that
\nmemory loss can be reversed by diet and lifestyle. Vital Choice. October
\n 9, 2014.<\/p>\n

<\/p>\n

Blood Type Relates to Memory<\/strong><\/p>\n

People
\n with blood type AB may be more likely to develop memory loss in later
\nyears than people with other blood types, according to a study. AB is
\nthe least common blood type, found in about 4 percent of the U.S.
\npopulation. The study found that people with AB blood were 82 percent
\nmore likely to develop the thinking and memory problems that can lead to
\n dementia than people with other blood types.<\/em><\/p>\n

American
\nAcademy of Neurology (AAN). Can your blood type affect your memory in
\nlater years? Science Daily. September 10, 2014.
\nhttp:\/\/www.sciencedaily.com\/releases\/2014\/09\/140910185913.htm<\/p>\n

Kristine
\n S. Alexander, Neil A. Zakai, Sarah Gillett, Leslie A. Mcclure, Virginia
\n Wadley, Fred Unverzagt, and Mary Cushman. ABO blood type, factor VIII,
\nand incident cognitive impairment in the REGARDS cohort. Neurology,
\nSeptember 2014 DOI: 10.1212\/WNL.0000000000000844<\/p>\n

Neuroticism Linked to Alzheimer’s <\/strong><\/p>\n

A
\n population-based sample of 800 women, aged 38 to 54 years, was examined
\n in 1968, with subsequent examinations in 1974, 1980, 1992, 2000, and
\n2005. Neuroticism and extraversion were assessed using the Eysenck
\nPersonality Inventory at baseline. Distress was measured according to a
\nstandardized question at each study wave. Dementia was diagnosed
\naccording to DSM-III-R criteria based on information from
\nneuropsychiatric examinations, informant interviews, hospital records,
\nand registry data.<\/em><\/p>\n

CONCLUSIONS: <\/em><\/strong>Our
\n study suggests that midlife neuroticism is associated with increased
\nrisk of AD dementia, and that distress mediates this association. The
\nresults have clinical implications because a group of women at risk of
\nAD dementia is identified.<\/em><\/p>\n

Johansson L1, Guo X2, Duberstein
\nPR2, H\u00e4llstr\u00f6m T2, Waern M2, Ostling S2, Skoog I2. Midlife personality
\nand risk of Alzheimer disease and distress: A 38-year follow-up.
\nNeurology. 2014 Oct 1. pii: 10.1212\/WNL.0000000000000907. [Epub ahead of
\n print]<\/p>\n

Movement- For Improving Cognition and Brain Function in Kids<\/strong><\/p>\n

This
\n study of 221 children (ages 7-9 years) aimed to determine the effect of
\n a 9-month afterschool physical activity (PA) intervention on brain and
\nbehavioral indices of executive control in preadolescent children.<\/p>\n

…In
\n addition to changes in fitness (maximal oxygen consumption), electrical
\n activity in the brain (P3-ERP) and behavioral measures (accuracy,
\nreaction time) of executive control were collected by using tasks that
\nmodulated attentional inhibition and cognitive flexibility.<\/em><\/p>\n

CONCLUSIONS:
\n The intervention enhanced cognitive performance and brain function
\nduring tasks requiring greater executive control. These findings
\ndemonstrate a causal effect of a PA program on executive control, and
\nprovide support for PA for improving childhood cognition and brain
\nhealth.<\/em><\/p>\n

Hillman CH1, Pontifex MB2, Castelli DM3, Khan NA4,
\nRaine LB4, Scudder MR4, Drollette ES4, Moore RD4, Wu CT5, Kamijo K6.
\nEffects of the FITKids Randomized Controlled Trial on Executive Control
\nand Brain Function. Pediatrics. 2014 Oct;134(4):e1063-71. doi:
\n10.1542\/peds.2013-3219.<\/p>\n

Exercise, a New Treatment for ADHD?<\/strong><\/p>\n

The
\n goal of this study was to compare the effects of before school physical
\n activity (PA) and sedentary classroom-based (SC) interventions on the
\nsymptoms, behavior, moodiness, and peer functioning of young children (M
\n age<\/sub>?=?6.83) at risk for attention-deficit\/hyperactivity disorder (<\/em>A<\/em>DHD<\/em>-risk;
\n n?=?94) and typically developing children (TD; n? =?108). Children were
\n randomly assigned to either PA or SC and participated in the assigned
\nintervention 31 min per day, each school day, over the course of
\n12 weeks. Parent and teacher ratings of <\/em>ADHD<\/em> symptoms
\n(inattention, hyperactivity\/impulsivity), oppositional behavior,
\nmoodiness, behavior toward peers, and reputation with peers, were used
\nas dependent variables. Primary analyses indicate that the PA
\nintervention was more effective than the SC intervention at reducing
\ninattention and moodiness in the home context. Less conservative
\nfollow-up analyses within <\/em>ADHD<\/em> status and intervention groups suggest that a PA intervention may reduce impairment associated with <\/em>ADHD<\/em>-risk
\n in both home and school domains; interpretive caution is warranted,
\nhowever, given the liberal approach to these analyses. Unexpectedly,
\nthese findings also indicate the potential utility of a before school SC
\n intervention as a tool for managing <\/em>ADHD<\/em> symptoms.
\nInclusion of a no treatment control group in future studies will enable
\nfurther understanding of PA as an alternative management strategy for <\/em>ADHD<\/em> symptoms.<\/em><\/p>\n

Hoza,
\n B, Smith, A, Shoulberg, E, et al. A Randomized Trial Examining the
\nEffects of Aerobic Physical Activity on Attention-Deficit\/Hyperactivity
\nDisorder Symptoms in Young Children. J of Abnormal Child Psychology.
\nSeptember 10, 2014. Doi. 10.1007\/s10802-014-9929-y<\/p>\n

Hamblin, J.Exercise is ADHD Medication. The Atlantic. September 29, 2014.<\/p>\n

<\/p>\n

Exercise For Memory<\/strong><\/p>\n

Previous
\n studies have shown that memory may be improved by several months of
\naerobic exercises, such as running, cycling or swimming. However, the
\nfindings of the new study – published in the journal Acta Psychologica –
\n demonstrate that a similar memory boost can be achieved in a much
\nshorter period. <\/em><\/p>\n

“Our
\n study indicates that people don’t have to dedicate large amounts of
\ntime to give their brain a boost,” says Lisa Weinberg, the Georgia Tech
\ngraduate student who led the project. <\/em><\/p>\n

As
\n well as looking at aerobic exercise, Weinberg’s team also examined how
\nresistance exercise – weightlifting, push-ups and sit-ups – might affect
\n memory. <\/em><\/p>\n

The
\n team recruited 46 participants (29 women and 17 men), who were randomly
\n assigned into two groups. For the first part of the experiment, all
\nparticipants viewed a series of 90 images on a computer screen. <\/em><\/p>\n

McNamee. D. What kinds of exercise can boost long-term memory? Medical News Today. October 5, 2014.<\/p>\n

Inflammation and Depression Linked (Curcumin vs. NSAIDs)<\/strong><\/p>\n

The following is a review of the antidepressant and possible adverse effects of anti-inflammatory interventions.<\/p>\n

Data
\n Sources-Trials published prior to December, 31, 2013, were identified
\nsearching Cochrane Central Register of Controlled Trials, PubMed,
\nEMBASE, PsychINFO, Clinicaltrials.gov, and relevant review articles.<\/em><\/p>\n

Study
\n Selection- Randomized placebo-controlled trials assessing the efficacy
\nand adverse effects of pharmacologic anti-inflammatory treatment in
\nadults with depressive symptoms, including those who fulfilled the
\ncriteria for depression.<\/em><\/p>\n

Results-
\n Ten publications reporting on 14 trials (6262 participants) were
\nincluded: 10 trials evaluated the use of nonsteroidal anti-inflammatory
\ndrugs (NSAIDs) (n<\/em>?<\/em>=<\/em>?<\/em>4258) and 4 investigated cytokine inhibitors (n<\/em>?<\/em>=<\/em>?<\/em>2004). …<\/em><\/p>\n

Conclusions
\n and Relevance – Our analysis suggests that anti-inflammatory treatment,
\n in particular celecoxib, decreases depressive symptoms without
\nincreased risks of adverse effects. However, a high risk of bias and
\nhigh heterogeneity made the mean estimate uncertain. This study supports
\n a proof-of-concept concerning the use of anti-inflammatory treatment in
\n depression. Identification of subgroups that could benefit from such
\ntreatment might be warranted.<\/em><\/p>\n

Ole K\u00f6hler, et al. Effect of
\nAnti-inflammatory Treatment on Depression, Depressive Symptoms, and
\nAdverse EffectsA Systematic Review and Meta-analysis of Randomized
\nClinical Trials ONLINE FIRST. JAMA Psychiatry. Published online October
\n15, 2014. doi:10.1001\/jamapsychiatry.2014.1611<\/p>\n

Curcumin for Cognition Support<\/strong><\/p>\n

Curcumin
\n possesses many properties which may prevent or ameliorate pathological
\nprocesses underlying age-related cognitive decline, dementia or mood
\ndisorders. These benefits in preclinical studies have not been
\nestablished in humans. This randomized, double-blind, placebo-controlled
\n trial examined the acute (1 and 3 h after a single dose), chronic (4
\nweeks) and acute-on-chronic (1 and 3 h after single dose following
\nchronic treatment) effects of solid lipid curcumin formulation (400 mg
\nas Longvida\u00ae) on cognitive function, mood and blood biomarkers in 60
\nhealthy adults aged 60-85. One hour after administration curcumin
\nsignificantly improved performance on sustained attention and working
\nmemory tasks, compared with placebo. Working memory and mood (general
\nfatigue and change in state calmness, contentedness and fatigue induced
\nby psychological stress) were significantly better following chronic
\ntreatment. A significant acute-on-chronic treatment effect on alertness
\nand contentedness was also observed. Curcumin was associated with
\nsignificantly reduced total and LDL cholesterol and had no effect on
\nhematological safety measures. To our knowledge this is the first study
\nto examine the effects of curcumin on cognition and mood in a healthy
\nolder population or to examine any acute behavioral effects in humans.
\nResults highlight the need for further investigation of the potential
\npsychological and cognitive benefits of curcumin in an older population.
\n <\/em><\/p>\n

Cox, K, Pipingas, A, & Scholey, A. Investigation of the
\n effects of solid lipid curcumin on cognition and mood in a healthy
\nolder population. J Psychopharmacol. October 2, 2014. Doi:
\n0269881114552744<\/p>\n

<\/p>\n

Tumeric For (Rodent) Brain Growth<\/strong><\/p>\n

In
\n a recent rodent study, a bioactive compound found in turmeric promoted
\nstem cell proliferation and differentiation in the brain.<\/em><\/p>\n

…<\/em><\/p>\n

To
\n test the effects of ar-turmerone on NSC in vivo, the researchers
\ninjected adult rats with ar-turmerone. Using PET imaging and a tracer to
\n detect proliferating cells, they found that the subventricular zone
\n(SVZ) was wider, and the hippocampus expanded, in the brains of rats
\ninjected with ar-turmerone than in control animals. The SVZ and
\nhippocampus are the two sites in adult mammalian brains where
\nneurogenesis, the growth of neurons, is known to occur.<\/em><\/p>\n

FARS News Agency.Turmeric Compound Boosts Regeneration of Brain Stem Cells. Life Extension. September 29, 2014. http:\/\/www.lef.org\/news\/lefdailynews?NewsID=22917&Section=DISEASE<\/p>\n

Hucklenbroich
\n J, Klein R, Neumaier B, Graf R, Fink G, et al. Aromatic-turmerone
\ninduces neural stem cell proliferation in vitro and in vivo. Stem Cell Research & Therapy. <\/em>2014.<\/p>\n

Castillo, S. Turmeric Helps Your Brain Heal Itself: Spice Up Your Brain Power With Curry. Medical News Today. Sep 26, 2014. http:\/\/www.medicaldaily.com\/turmeric-helps-your-brain-heal-itself-spice-your-brain-power-curry-305242<\/p>\n

Also, be sure to check out all the updates on health, lifestyle, wellness, food & nutrition, and drug updates on my homepage.<\/b><\/p>\n

Until next time, keep educating and empowering your health and brain!
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In a few days I'll heading off to to learn all about one of my favorite subjects, the gut, from some of the top integrative doctors in the world. 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She became interested in holistic medicine when she was able to heal two herniated discs through nutrition, yoga, supplementation, and chiropractic. She has mentored with holistic practices throughout New York, Vermont, and Connecticut. In addition to her Naturopathic and Functional Medical training, Dr. LoBisco has extensive training in a variety of healing modalities, including therapeutic essential oils, nutraceuticals, herbs, whole food supplements, nutritional medicine, and mind-body therapies. She is a graduate of the accredited, four year post-graduate program in Naturopathic Medicine at the University of Bridgeport in Connecticut. This program includes clinical rotations and a demanding scientific curriculum in integrating conventional and natural medicine. Dr. LoBisco holds her license from the state of Vermont. Dr. LoBisco has completed her postdoctoral training as a certified functional medicine practitioner. She is also certified in Applied Kinesiology and holds a BA in psychology from SUNY Geneseo. She has contributed as an item writer for the North American Board of Naturopathic Examiners (NABNE) and has several articles that have been published in the Naturopathic Doctor News and Review Digest (NDNR) and the Townsend Letter, both physician- based journals. Dr. LoBisco is also a hired speaker on integrative medical topics for medical professionals. Dr. LoBisco currently incorporates her training in holistic medical practices and conventional medicine through writing, researching, private practice, and through her independent contracting work for companies regarding supplements, nutraceuticals, essential oils, and medical foods. She has a small, private wellness consultation practice through telephone and Skype. Dr. LoBisco also enjoys continuing to educate and empower her readers through her blogs and social media. Her new book, BreakFree Medicine, is now available on Amazon and through Barnes & Noble.","url":"https:\/\/www.saratoga.com\/living-well\/author\/slobisco\/"}]}},"_links":{"self":[{"href":"https:\/\/www.saratoga.com\/living-well\/wp-json\/wp\/v2\/posts\/15872"}],"collection":[{"href":"https:\/\/www.saratoga.com\/living-well\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.saratoga.com\/living-well\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.saratoga.com\/living-well\/wp-json\/wp\/v2\/users\/109"}],"replies":[{"embeddable":true,"href":"https:\/\/www.saratoga.com\/living-well\/wp-json\/wp\/v2\/comments?post=15872"}],"version-history":[{"count":1,"href":"https:\/\/www.saratoga.com\/living-well\/wp-json\/wp\/v2\/posts\/15872\/revisions"}],"predecessor-version":[{"id":27599,"href":"https:\/\/www.saratoga.com\/living-well\/wp-json\/wp\/v2\/posts\/15872\/revisions\/27599"}],"wp:attachment":[{"href":"https:\/\/www.saratoga.com\/living-well\/wp-json\/wp\/v2\/media?parent=15872"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.saratoga.com\/living-well\/wp-json\/wp\/v2\/categories?post=15872"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.saratoga.com\/living-well\/wp-json\/wp\/v2\/tags?post=15872"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}